* arthroplasty registry NJR6
We thank the patients and staff of all the hospitals in England, Wales, Northern Ireland and the Isle of Man who have contributed data to the National Joint Registry. We are grateful to the Healthcare Quality Improvement Partnership (HQIP), the NJR Steering Committee and staff at the NJR Centre for facilitating this work. The views expressed represent those of Heraeus Medical GmbH and do not necessarily reflect those of the National Joint Registry Steering Committee or the Health Quality Improvement Partnership (HQIP) who do not vouch for how the information is presented.
3 Meinardi JE, et al. Palacos compared to Palamed bone cement in total hip replacement: a randomized controlled trial. Acta Orthop 2016; 87(5): 473–478.
4 Trela-Larsen L, et al. The association between cement type and the subsequent risk of revision surgery in primary total hip replacement. Acta Orthop 2018; 89(1): 40–46.
5 Adalberth G, et al. Fixation of the tibial component using CMW-1 or Palacos bone cement with gentamicin: similar outcome in a randomized radiostereometric study of 51 total knee arthroplasties. Acta Orthop Scand 2002; 73(5): 531–538.
6 NJR 19th Annual Report 2022: Surgical data to 31 December 2021; 3.
7 NJR Implant Summary Report for Heraeus Medical GmbH. Primary Hips using PALACOS® Antibiotic Cement: 08/2023. Page 4 and 10. Current reports accessible at http://herae.us/njr-data.
8 NJR Implant Summary Report for Heraeus Medical GmbH. Primary Knees using PALACOS® Antibiotic Cement: 08/2023. Page 4 and 6. Current reports accessible at http://herae.us/njr-data.
9 Kuehn KD.: PMMA Cements – Are we aware what we are using? Heidelberg: Springer Verlag, 2014.
10 Kuehn KD. PMMA Cements – Are we aware what we are using? Springer Verlag 2014; 106–107.
11 Kuehn KD, Hoentzsch D. Augmentation mit PMMA-Zement. Der Unfallchirurg 2015; 118(9): 737–748.
12 Berberich CE, Josse J, Laurent F, Ferry T. Dual antibiotic loaded bone cement in patients at high infection risks in arthroplasty: Rationale of use for prophylaxis and scientific evidence. World J Orthop 2021; 12(3):119–28.
13 Gehrke, T., von Förster, G., Frommelt, L. (2001). Pharmacokinetic Study of a Gentamicin/Clindamicin Bone Cement Used in One-stage Revision Arthroplasty. In: Walenkamp, G.H.I.M., Murray, D.W., Henze, U., Kock, HJ. (eds) Bone Cements and Cementing Technique. Springer, Berlin, Heidelberg.
14 Sanz-Ruiz P., Berberich C. Infection Risk-Adjusted Antibiotic Prophylaxis Strategies in Arthroplasty: Short Review of Evidence and Experiences of a Tertiary Center in Spain. OrthopRes Rev. 2020 Aug 6; 12: 89–96.
15 Abdelaziz H. et al. M. Minimum 5 years‘ follow-up after gentamicin- and clindamycin-loaded PMMA cement in total joint arthroplasty. J Med Microbiol. 2019 Mar;68(3):475–479.
16 Sprowson A.P. et al. The use of high-dose dual-impregnated antibiotic-laden cement with hemiarthroplasty for the treatment of a fracture of the hip: The Fractured Hip Infection trial. Bone Joint J. 2016 Nov;98- B(11):1534-41.6F.
17 Savage P. et al. Arthroplasty infection rates in fractured neck of femur: single vs dual antibiotic cement. Ann R Coll Surg Engl. 2019 Sep;101(7):514–518.
18 Tyas B, Marsh M, Oswald T, Refaie R, Molyneux C, Reed M. Antibiotic resistance profiles of deep surgical site infections in hip hemiarthroplasty; comparing low dose single antibiotic versus high dose dual antibiotic impregnated cement. J Bone Jt Infect. 2018;3(3):123-9.
19 Sanz-Ruiz P. et al. Is Dual Antibiotic-Loaded Bone Cement More Effective and Cost Efficient Than a Single Antibiotic-Loaded Bone Cement to Reduce the Risk of Prosthetic Joint Infection in Aseptic Revision Knee Arthroplasty? J Arthroplasty. 2020 Dec; 35(12): 3724–3729.
